A Prothrombin Activator Serine Protease from the Lonomia obliqua Caterpillar Venom (Lopap): Biochemical Characterization
Abstract Lonomia obliqua venom causes a severe consumptive coagulopathy, which can lead to a hemorrhagic syndrome. The crude bristles extract displays a procoagulant activity due to a Factor X and to a prothrombin activating activity. Here, we describe a 69 kDa prothrombin activator serine protease purified from L. obliqua caterpillar bristle extract using gel filtration … Read more